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Drug-induced hyperthermia : ウィキペディア英語版 | Drug-induced hyperthermia Drug-induced fever is a symptom of an adverse drug reaction wherein the administration of drugs intended to help a patient causes a hypermetabolic state resulting in fever. The drug may interfere with heat dissipation peripherally, increase the rate of metabolism, evoke a cellular or humoral immune response, mimic endogenous pyrogen, or damage tissues. ==Triggers==
* Directly caused by the drug,'' e.g.'' lamictal, progesterone, or chemotherapeutics causing tumor necrosis * Possible side effect of stimulants and entactogens (e.g. cocaine, MDMA, methamphetamine, PMA, 4-MTA) * As an adverse reaction to drugs, ''e.g.'' antibiotics or sulfa drugs. * After drug discontinuation, ''e.g.'' heroin or fentanyl withdrawal * Neuroleptic Malignant Syndrome; rare, life-threatening hyperpyrexia caused by antidopaminergic drugs (mostly antipsychotics) * Serotonin Syndrome; excessive serotonergic activity due usually to combined use of serotonergic drugs (e.g. antidepressants, stimulants, triptans) * 5HT2A agonists, ''e.g.'' psilocybin or LSD * Malignant_hyperthermia
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